LigandTracer monitors interactions as they happen; detecting interaction properties that can easily be missed by using established endpoint methods such as ELISA. Data points are taken automatically at set intervals, allowing you to obtain in-depth information about the interaction that you’re studying.
LigandTracer Green – Detects Fluorescence
LigandTracer Green is made for cell-biologists. Introducing time into the binding assay results in more detailed and robust characterization of interactions.
Key features
- Monitor the dynamics of protein-cell interactions in real-time, both during incubation and after wash
- Flexible platform compatible with a large number of applications with protein binding to receptors on living cells being the most common
- Derive the affinity, on/off-rate, specificity and dose/time dependent target occupancy
- Interchangeable detectors for different sets of fluorophores
- Interactive self-learning package included
- Affordable, easy to use and saves labor time
- Maintenance free and low running costs
LigandTracer Yellow – Detects High Energy ɣ Photons
LigandTracer Yellow is designed to speed up the development of medical imaging agents by providing not only the affinity of tracers to cellular targets but also valuable information on the interaction mechanism. Equipped with a high energy ɣ scintillator-based detector suitable for all radionuclides used in PET/SPECT imaging, real-time binding assays is made possible.
Key features
- Detect ligand-cell interactions and cellular uptake in real-time using PET/SPECT tracers
- Flexible platform compatible with a large number of applications with radioligand binding to receptors on live cells being the most common
- Derive the affinity, on/off-rate, specificity and dose/time dependent target occupancy
- Interactive self-learning package included
- Affordable, easy to use and saves labor time
- Maintenance free and low running costs
- Measure in incubator, room temperature or cold room
LigandTracer Grey – Detects Low Energy ɣ Photons
LigandTracer Grey measures interactions on live cells, minute by minute, during and after incubation. The binding curve displays the amount of cell associated ligand over time, and contains information about affinity, kinetics and the interaction mechanism.
Key features
- Monitor the dynamics of protein-cell interactions in real-time, using proteins labeled with low energy ɣ-emitting radionuclides such as 125I
- Derive the affinity, on/off-rate, specificity and dose/time dependent target occupancy
- Interactive self-learning package included
- Affordable, easy to use and saves labor time
- Maintenance free and low running costs
- Measure in incubator, room temperature or cold room
LigandTracer White – Detects Beta+/- Particles
LigandTracer White detects β– and β+ particles from atoms embedded in the molecular structure such as 11C/14C, 32P/33P and 35S and beta emitting halogens and metals. LigandTracer White is for example used to follow 18F-FDG or 11C-acetate uptake as well as interaction studies to cellular receptors of small molecules and radioligands suitable for PET imaging and cancer therapy.
Key features
- Flexible platform compatible with a large number of applications with radioligands binding to receptors on live cells being the most common
- Derive the affinity, on/off-rate, specificity, dose/time dependent target occupancy and cellular uptake/retention
- Interactive self-learning package included
- Affordable, easy to use
- Maintenance free and low running costs
- Measure in incubator, room temperature or cold room